The main objective of the study is to develop and to create a parametric model to be behind of a new methodology based on an analysis of relief and environmental factors that play a decisive role in expanding of a ski area. There are two aspects: analysis of the relief parameters (hypsometry, geodeclivity, slope exposition, geology, land use, soil) and analysis of the climatic factors (snow thickness, average annual temperature). Each parameter is analysed, classified according to common features, reclassified into categories of suitability and introduced into a model that has the result a map of suitability for the development of the ski area. The methodology has as novelty the fact that it has an applicable model to any space and can be used by the authorities interested in the arrangement, development or design of the ski areas.\nThis result is particularly important and useful for local authorities because in government programs for investment in ski area development, local authorities are the ones that identify new potential areas.

Prevalence of type 2 diabetes mellitus patient are increased every year. The role of medicinal plant against diseases is still questionable. Salam (Eugenia polyantha) and Sambiloto (Andrographidis folium) leaves increase glucose intake into the body cells. This property have been use by people to decrease their blood glucose concentration. The aim of this study is to analyze the affect of salam and sambiloto leaves to lower blood glucose concentration on type 2 diabetes mellitus patient. Clinical test with before and after design was used as method. Sample was designed by concecutive sampling with inclution and exclution concideration. Total subject of this study are 40 people that have type 2 diabetes mellitus diagnose. Subjects were divided to two group and each group consist of 20 people. One group consumed salam leaves and sthe other one consumed sambiloto leaves. 300 mg of this medicinal plants was given as capsule. The presciption was 1-2 capsule per day for one week. During this study, we observed several parameter include: patient characteristic, blood glucose concentration (GD2JPP), uric acid, total cholesterol, blood pressure and other sucjective complaints. The result showed that Salam (Eugenia polyantha) and Sambiloto (Andrographidis folium) leaves can lower blood glucose concentration on type 2 diabetes mellitus patient significantly (p<0,05). Besides lowering level blood glucose concentration by 26-32%, they can control uric acid, cholesterol total, and blood pressure, sinergistically.

The stability of rock slopes of the walls of Roodbar dam in Lorestan is investigated using multi-layer Perceptron of artificial neural network algorithm. Then, the stability of rock slopes is studied by considered factors affecting stability at before and after impounding dam. The calculation is done on the factors affecting stability using artificial neural network algorithm. Finally, the results show that rock slopes of the walls of Roodbar dam in Lorestan in a dry state are stable at seventeen modes and unstable at three modes. Also, in a saturated state are stable at fourteen modes and unstable at six modes, furthermore have generally a little stability. The results of this paper indicated that the calculation of this algorithm has suitable results for this matter.

Cefotaxime enriched with impurities was evaluated for its capacity to induce mutations at thymidine kinase (TK) locus in mouse lymphoma L5178Y TK+/- cell lines. Five test concentrations of 105, 209, 417, 833 and 1665 µg/ml were chosen for the range finding study. The maximum concentration (1665 µg/ml) was limited by solubility of the test substance in Dimethyl sulphoxide (DMSO). The stock solution (100x) of the test substance was diluted 1 in 100 in culture medium to achieve the desired final concentrations. For 3-hour treatment in the presence of S9 the %RTG ranged between 114.7 and 10.1; and for 3-hour treatment in the absence of S9 the %RTG ranged between 144.7 and 36.79. For 24-hour treatment in the absence of S9, the %RTG ranged between 73.4 and 1.95. The concentrations were selected for the main mutation experiments: 3-hour, -/+S9: 50, 100, 500, 1000, 1500, 2000, 2500 and 3330 µg/ml, 24-hour, -S9: of 50, 100, 250, 500, 750, 1000, 1250 and 1500 µg/ml. It should be noted that for the 3-hour treatments, it was decided to go for concentrations higher than 1665 µg/ml. The stock solution (100 xs) of the test substance was diluted 2 in 100 in culture medium to achieve the desired final concentrations. The assays were therefore considered valid. In all three treatment regimes (3-hour, +/-S9 and 24-hour, -S9), treatment of cultures with cefotaxime enriched with impurities, resulted in an acceptable (6.50 to 14.76%) dose related decrease in %RTG. The mutant frequencies of all cefotaxime enriched with impurities treated cultures fell within or close to the historical control values and were not significantly different from the concurrent negative control cultures. Furthermore, there was no dose related increase in mutant frequencies associated with Cefotaxime enriched with impurities treatments. It is concluded, that under the conditions of the test, cefotaxime enriched with impurities did not induce mutations in L5178Y cells when tested upto concentrations inducing acceptable levels of cytotoxicity.

In this study, some reproductive parameters of the non-native silver crucian carp \n(Carassius gibelio) from Seyhan Dam Lake were investigated. Samplings were \nconducted monthly through trammel nets between June 2013 and May 2014. A total of \n540 individuals were investigated, and among them 10 (1.85%) were males, 530 (98.15%) \nof them were females. The length at first maturation was detected as 16.8 cm TL. \nAccording to maturation stages of female gonads; ripe females were found to be present \nbetween February-July. Intense spawning periods are in spring during March, April and \nMay. The biggest egg diameter was found as 1.32 mm in March and the highest number \nof eggs was found as 347550. \nSilver crucian carp displayed a great reproductive output in Seyhan Dam Lake and the \ngiven reservoirs have been completely invaded.

This work aimed at characterizing fixed oil of the lentisk tree (Pistacia lentiscus L.) from four regions in northern Tunisia. A chemical characterization of the different samples of oil was carried out by determining its fatty acid composition, quality index, structural indexes, refractive index, vitamin E content and fat content. The chemical analyses showed that this oil is rich in oleic acid (46.30%), linoleic acid (22.65%) and palmitoleic acid (1.65%). The various parameters and indexes of quality and structure obtained are: acid index (21.86), peroxide index (14.88), saponification index (176.02), iodine value (8.70), Refractive index (1.4658475), water content (3.04%), content of insoluble impurities (2.05%) and fat content (97.05%). The oil is also rich in alpha tocopherol (45.63 mg / 100g) and gamma tocopherol (20.17 mg / 100g). These results indicate that the composition of the fixed oil is not dependent on the origin of the lentisk tree, but rather on the individual tree and the processing of the fixed oil. Therefore, it is important to take the necessary precautions, such as avoiding contamination, while processing the oil and also that individual trees need constant monitoring and care so as to ensure maximum growth potential.